Omega-3 (EPA/DHA) for longevity
Grade ALong-chain marine fatty acids with consistent cardiovascular, neurologic, and inflammatory benefits.
91/100 Evidence Strength
Why Omega-3 (EPA/DHA) matters for longevity
Long-chain marine fatty acids with consistent cardiovascular, neurologic, and inflammatory benefits.
- Triglyceride reduction
- Lower atherosclerotic event risk in higher-risk groups
- Mood and cognition support
Typical dose
2 g EPA/DHA combined
Best timing
With largest meal
Evidence grade
Grade A 91/100
Mechanism of action
Incorporated into membrane phospholipids; precursors to resolvins and protectins; lower hepatic triglyceride synthesis.
Dosage & Timing
Typical
2 g EPA/DHA combined
Range
1–4 g
Timing
With largest meal
With Food
Yes
Form
Triglyceride-form fish oil or algal DHA
Category
Cardiovascular
Reported Benefits
- Triglyceride reduction
- Lower atherosclerotic event risk in higher-risk groups
- Mood and cognition support
Side Effects
- Fishy reflux
- Mild platelet effects at high doses
Contraindications
- Bleeding disorders without supervision
Known Interactions
Anticoagulants (warfarin)Monitor INR; additive effect possible.
References
Omega-3 (EPA/DHA) — Frequently Asked Questions
Common questions about dose, benefits, side effects and longevity use of Omega-3 (EPA/DHA).
What is the typical dose of Omega-3 (EPA/DHA)?+
2 g EPA/DHA combined (range 1–4 g). With largest meal. Take with food.
How does Omega-3 (EPA/DHA) work in the body?+
Incorporated into membrane phospholipids; precursors to resolvins and protectins; lower hepatic triglyceride synthesis.
What are the longevity benefits of Omega-3 (EPA/DHA)?+
Long-chain marine fatty acids with consistent cardiovascular, neurologic, and inflammatory benefits. Reported benefits include: Triglyceride reduction; Lower atherosclerotic event risk in higher-risk groups; Mood and cognition support.
What are the side effects of Omega-3 (EPA/DHA)?+
Fishy reflux; Mild platelet effects at high doses Avoid in: Bleeding disorders without supervision.
What is Omega-3 (EPA/DHA) commonly stacked with for longevity?+
Vitamin D3, Astaxanthin.
Comparison vs Alternatives
All Supplements →| Attribute | Omega-3 (EPA/DHA)This page | Creatine Monohydrate | Magnesium Glycinate |
|---|---|---|---|
| Evidence | Grade A91/100 | Grade A94/100 | Grade A89/100 |
| Category | Cardiovascular | Cognition | Sleep |
| Best for | Triglyceride reduction | Strength and lean mass | Improved sleep latency and HRV |
| Typical dose | 2 g EPA/DHA combined | 5 g daily | 300–400 mg elemental PM |
| Timing | With largest meal | Any time of day, consistent | 60 min before bed |
| Form | Triglyceride-form fish oil or algal DHA | Micronized powder | Capsule or powder |
| Action | Current page | View → | View → |