The synthesized longevity record.
1,200+ peer-reviewed studies indexed, graded and cross-referenced. Updated daily with the most consequential findings in healthspan science.
Rhodiola Rosea: Unpacking its Mechanism of Action for Stress Resilience
This paper investigates the molecular mechanisms through which Rhodiola rosea exerts its adaptogenic effects, focusing on HPA axis modulation, neuroprotection, and cellular stress responses.
NMN vs NR: Which NAD+ Precursor Wins for Adult Restoration?
Head-to-head review of nicotinamide mononucleotide and nicotinamide riboside — pharmacokinetics, NAD+ uplift, human trial endpoints, and dosing strategy.
Time-Restricted Eating and Metabolic Flexibility: The 2026 Evidence
What 14 years of randomized trials reveal about TRE windows, circadian alignment, insulin sensitivity, and lean mass preservation.
Intermittent Rapamycin in Healthy Adults — The PEARL Trial
Inside the largest randomized trial of low-dose rapamycin for healthspan: dosing schedule, lean-mass and pain outcomes, immune signals, and what it does and does not prove.
Retatrutide Beyond Weight Loss: Cardiometabolic and Longevity Signals
The first triple GIP/GLP-1/glucagon agonist is generating obesity, hepatic, and cardiometabolic data that already exceed any prior incretin — and points to a broader longevity signal.